Gene Expression and Embryogenesis in Amphibians
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Expressional Analysis of Stem Cell Marker SALL4 in Mesencephalon during Chicken Embryogenesis
Background SALL gene family represent a group of evolutionary conserved zinc finger transcription factors which are involved in normal development. It includes four members (SALL1 to SALL4). SALL4 has significant roles in the maintenance of pluripotency and self-renewal, efficient proliferation /stabilization and cell fate decision of embryonic stem cells (ESCs). Our aim in this study was to a...
متن کاملGENETICS AND MOLECULAR BIOLOGY - Gene Expression and Embryogenesis in Amphibians - Horst Grunz ©Encyclopedia of Life Support Systems (EOLSS) GENE EXPRESSION AND EMBRYOGENESIS IN AMPHIBIANS
Contents 1. Introduction 2. Historical background 3. The search for inducing factors 3.1 Isolation of the first embryonic inducing factor from chicken embryos – a milestone for our understanding of evolutionary conserved proteins 3.2 The search for neuralizing factors 4. The Responding Tissue 5. Autoneuralization and the Neural Default Hypothesis 6. Organizer and Antiorganizers 7. The importanc...
متن کاملExpression of hsp90 Alpha and hsp90 Beta during Xenopus laevis Embryonic Development
Background: Members of the eukaryotic Hsp90 family function as important molecular chaperones in the assembly, folding and activation of cellular signaling in development. Two hsp90 genes, hsp90 alpha and hsp90 beta, have been identified in fish and homeothermic vertebrates but not in poikilothermic vertebrates. In the present study, the expression of hsp90 alpha and hsp90 beta genes in Xenopus...
متن کاملIntegrin Linked Kinase (X-ILK) Function during Embryonic Development and within Adult Tissues of Xenopus laevis
Integrin linked kinase (ILK) is a serine/threonine protein kinase implicated in the phosphatidylinositol 3’kinase (PI3’K) pathway. Integrin linked kinase has been investigated in different organisms such as mammalian systems (human, mice, rat), insects (Drosophila) and nematodes (Cenorhabditis elegans), however to date little data regarding ILK research on amphibians has been reported. In...
متن کاملP-157: Polymorphic Core Promoter GA-repeats Alter Gene Expression of The Early Embryonic Developmental Genes
Background: We examine the GA-repeat core promoters of MECOM and GABRA3 in human embryonic kidney-293 cell line and show that those GA-repeats have promoter activity,and those different alleles of the repeats can significantly alter gene expression.We propose a novel role for GA-repeat core promoters to regulate gene expression in the genes involved in development and evolution. Materials and M...
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تاریخ انتشار 2011